Remember the tea kettle – it is always up to its neck in hot water, yet it still sings!
Children whose mothers abused methamphetamine during their pregnancy show abnormalities in their brain. These abnormalities may be more severe than prenatal exposure to alcohol. The results of a new study are published this week in The Journal of Neuroscience. The study identifies vulnerable brain structures that may help predict learning and behavioral problems in children exposed to methamphetamine.
“We know that alcohol exposure is toxic to the developing fetus and can result in lifelong brain, cognitive, and behavioral problems,” said Elizabeth Sowell, PhD, of the University of California, Los Angeles, who led the study. “In this study, we show that the effects of prenatal meth exposure, or the combination of meth and alcohol exposure, may actually be worse. Our findings stress the importance of drug abuse treatment for pregnant women,” Sowell said.
The caudate nucleus, the area of the brain that controls learning, memory, motor control and motivation, was one of the areas more affected by methamphetamine abuse than alcohol exposure. According to data from the National Surveys on Drug Use and Health, 19,000 pregnant women reported using methamphetamine. About of the women who say they used the drug during pregnancy also used alcohol, so isolating the effects of methamphetamine on the developing brain is difficult.
The research team evaluated the specific effects of prenatal methamphetamine exposure by comparing MRIs of the brain of 61 children – 21 with prenatal methamphetamine and alcohol exposure, 13 with heavy alcohol exposure only, and 27 children that were not exposed to any substance. The MRIs showed that the sizes and shapes of certain brain structures varied depending on the prenatal drug exposure.
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